October 23, 2025
This question sparked many ideas and discussions during the recent meeting of the Mission Cancer Cluster on Diagnosis and Treatment, held in Berlin at Charité – Universitätsmedizin Berlin.
Projects such as LIVERATION, LEGATO, CARE1, DE-ESCALATE, IMPORTANT, SALVOVAR, Strexit2, PragmaTIL, IMPACT-AML, IntReall, and the newcomer FORCE Consortium, joined both in person and online to discuss challenges, potential solutions, and ongoing activities — all with a shared goal: to make pragmatic clinical trials work for the future.
During the meeting, work from the Citizen Engagement Working Group was presented — an initiative carried out over the past year by SHINE 2Europe and the Avedis Donabedian Foundation (LIVERATION). The presentation stressed the need for more time and resources in these projects to truly invest in involving citizens and patients, and in assessing Patient-Reported Outcome Measures (PROMs) and Quality of Life. However, the current administrative and regulatory burden makes this work particularly challenging.
The meeting highlighted a strong need for change and generated valuable recommendations, thanks to the contributions of highly engaged and motivated researchers and clinicians — in a space full of insightful and enthusiastic discussions.
